Please note: **The CFS has not been widely validated in younger populations (below 65 years of age), or in those with learning disability. It may not perform as well in people with stable long term disability such as cerebral palsy, whose outcomes might be very different compared to older people with progressive disability. We would advise that the scale is not used in these groups. However, the guidance on holistic assessment to determine the likely risks and benefits of critical care support, and seeking critical care advice where there is uncertainty, is still relevant.**
Frailty & COVID-19: why, what, how, where & when?
Rapid NICE guidance produced in response to the COVID outbreak clearly outlines the importance of identifying and grading frailty using the Clinical Frailty Scale. The purpose is to identify patients who are at increased risk of poor outcomes and who may not benefit from critical care interventions.
Frailty is a state of increased vulnerability to poor resolution of homoeostasis after a stressor event, which increases the risk of adverse outcomes(1). It can be assessed quickly and simply using the Clinical Frailty Scale (Appendix 1). Frailty identification should take no more the one minute(2); the more you use the scale, the quicker it will become.
The CFS is a reliable predictor of outcomes in the urgent care context (Appendix 2)(3-9); critical care specific outcomes are summarised in Appendix 3. Like any decision support tool, is not perfect and should not be used in isolation to direct clinical decision making. It will sensitise you to the likely outcomes in groups of patients, but clinical decision making with individual patients should be undertaken through a more holistic assessment, using the principles of shared decision making.
The CFS can be undertaken by any appropriately trained healthcare professional (doctor, nurse, health care assistant, therapist etc.) with training and support.
Ask the patient or their carer/next of kin/paramedics/care home staff what their capability was TWO weeks ago.
DO NOT base your assessment on how the patient appears before you today.
Decision makers using the CFS to inform clinical management MUST check the score to ensure that it is accurate.
DO be careful about differentiating between CFS 6 and 7:
CFS 6 (need help with outdoor activities and some help with basic activities) – all cause mortality during admission to acute hospital = 6%
CFS 7 (completely dependent for personal care) – all cause mortality during admission to acute hospital = 11%
The CFS should be assessed at ED triage, or any first point of contact with acute care (including by paramedics), alongside Early Warning Scores. It should be reassessed after two weeks if clinically relevant.
Online training resources
The AIMS Research Group at the Ottawa Hospital, Canada has developed a CFS Training Module that is freely accessible online that is useful in learning to administer the CFS. It seeks to provide learners with a comprehensive understanding of frailty and how to accurately determine a person's CFS score based on their specific circumstances.
Access overview >>
Using CFS in practice
DO remember that the CFS has only been validated in older people; it has not been widely validated in younger populations (below 65 year of age), or in those with learning disability. It may not perform as well in people with stable long term disability such as cerebral palsy, whose outcomes might be very different compared to older people with progressive disability. We would advise that the CFS is not used in these groups.
However, the guidance on holistic assessment to determine the likely risks and benefits of critical care support, and seeking critical care advice where there is uncertainty, is still relevant.
Ask the patient, their carer/next of kin/paramedics/care home staff what the patient’s capability was TWO weeks ago. The assessment should NOT be based on how the patient appears before you today. Decision makers using the CFS to inform clinical management MUST check the score to ensure that it is accurate.
Top tips to help you use the CFS
Professor Ken Rockwood
and colleagues have written a paper on COVID-19,
frailty and long-term care, and the potential implications for policy and
practice, which can be found here
There follows a series of short film clips about using the CFS in practice, and a longer TED talk from one of our AFN clinical leads, Dr Jay Banerjee:
Professor Ken Rockwood, Dalhousie University Canada – Use of the CFS: here
Alice Warren, Staff Nurse, ED, Leicester Royal Infirmary: here
Anuja Chalishazar, Junior Doctor, ED, Leicester Royal Infirmary: here
Jay Banerjee, Consultant in Emergency Medicine, ED, Leicester Royal Infirmary: here
Jay Banerjee, Consultant in Emergency Medicine, ED, Leicester Royal Infirmary, TedxLeicester talk on Living to Die:here
Examples of useful tools/resources
Royal Surrey Triage Decision Tool for use in Covid-19 Pandemic.pdf
COVID-19 Single Clerking Proforma - Royal Surrey.pdf
Appendix 1: Clinical Frailty Scale
The Clinical Frailty Scale was developed at Dalhousie University in Halifax, Nova Scotia Canada. The license is free for research, educational, and not-for-profit health care. Users are asked to sign a form agreeing not to change or commercialize it. Request / correspondence can be sent to the Geriatric Medicine Research Unit firstname.lastname@example.org
Appendix 2: Outcomes in acute care (NOT COVID specific) associated with frailty
Below are (unpublished) data displaying the time to death from ED attendance for different frailty scores, over two years.
Figure 1 Kaplan-Meier survival plot for time from ED arrival to death, by CFS category, nr = not recorded:
Frailty measured using the CFS or Frailty Index is associated with higher in-hospital (relative risk (RR) 1.7) and long-term mortality (RR 1.5)(10). Frail patients were less likely to be discharged home than fit patients (RR 0.6)(11). Additional studies undertaken since these reviews support the importance of frailty as a prognostic marker (Table 1).
Table 1 Outcomes from ICU using frailty as a predictor
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3. Cardona M, Lewis ET, Kristensen MR, et al. Predictive validity of the CriSTAL tool for short-term mortality in older people presenting at Emergency Departments: a prospective study. Eur Geriatr Med 2018;9(6):891-901. doi: 10.1007/s41999-018-0123-6 [published Online First: 2018/12/24]
4. Romero-Ortuno R, Wallis S, Biram R, et al. Clinical frailty adds to acute illness severity in predicting mortality in hospitalized older adults: An observational study. Eur J Intern Med 2016;35:24-34. doi: 10.1016/j.ejim.2016.08.033 [published Online First: 2016/09/07]
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